Psychotic comorbidities studies of individuals with diagnoses of major depression with psychotic features, as well as schizophrenia, reveal that minocycline not only attenuates some depression, but also the psychotic features.

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Caution in significant renal impairmentmay lead to azotemiahyperphosphatemiaand acidosismonitor BUN)

Take the missed dose as soon as you remember itHoweverif it is almost time for the next doseskip the missed dose and continue your regular dosing scheduleDo not take a double dose to make up for a missed one.

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Minocycline should be used with caution with oral contraceptives because it may decrease the effectiveness of oral contraceptives.

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